![]() They described their findings in the journal Scientific Reports.Īnalyses based on single nucleotide polymorphisms (SNPs) or point mutations showed that P. To gain more insights into the genomic diversity and population dynamics of Plasmodium falciparum, the deadliest malaria parasite in humans, Kaneko and his collaborators generated whole genome sequence data from 48 parasite isolates and compared them with parasites from other parts of Africa. “A comprehensive picture of a population of parasites requires an understanding of them on the individual genome level,” says Professor Akira Kaneko of the Department of Parasitology, Osaka City University Graduate School of Medicine.įor the past decade, Professor Kaneko and his collaborators have conducted various studies on malaria in and around Lake Victoria, Kenya, where the disease burden is among the highest in the country, to find ways to eliminate malaria successfully. ![]() To regain the momentum toward malaria elimination, scientists have increasingly turned to malaria parasite genomics to get a better understanding of the epidemiology and transmission dynamics, and the genetic basis underlying drug resistance and disease severity. On top of this, restrictions put in place to contain the COVID-19 pandemic have further limited malaria control programs such as mass bed net distribution and indoor residual spraying campaigns. Since 2016, progress in reducing malaria-related incidence and deaths over the past decade has been slowing down. Image: Local clinicians, laboratory technicians, and medical students from Osaka City University collect blood samples from students in a primary school on Mfangano Island to determine the prevalence of malaria infections. ![]()
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